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Injectable Cell-Derived Therapeutic to Stimulate Tissue Regeneration or Healing
Delivers Therapeutically Active Enhanced Secretome to Damaged Tissue to Promote Tissue RegenerationThis injectable minimally invasive treatment delivers enhanced secretome harvested from electrically stimulated cells to damaged tissue, thereby promoting tissue regeneration noninvasively. Biological cells and tissues produce a variety of proteins and...
Published: 6/27/2021
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Inventor(s): Christine Schmidt, Sahba Mobini
Keywords(s): electrical stimulation, Hydrogel, regenerative medicine, secretome, Therapeutic Application, Tissue Engineering
Category(s): Technology Classifications > Human Health Care > Therapeutics
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Magnetic Particle Conjugates for Remote Control of Tissue Formation
Controls Cell Activation Processes for Stem Cell Differentiation, Apoptosis or Tissue Matrix ProductionThese targeting agents use nucleic acid aptamers conjugated with magnetic nanoparticles to target cell surface receptors that make it possible to remotely control cell signaling for stem cell differentiation, apoptosis or tissue matrix production....
Published: 6/27/2021
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Inventor(s): Jon Dobson, Josephine Allen, Adam Monsalve
Keywords(s): Aptamer, Cell Activation, magnetic materials, Nanotechnology, Tissue Engineering
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Human Health Care > Others
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Magnetic Remote Targeting System for Controlling the Activity of Growth Factors
Provides Control of the Distribution and Activity of Growth Factors Used in Tissue Regeneration These magnetic nanoparticles conjugated with transforming growth factor beta (TGF-ß) and its latent complex accurately target delivery to specific locations and remotely activate or deactivate the growth factor, greatly augmenting the potential of TGF-ß...
Published: 6/27/2021
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Inventor(s): Jon Dobson, Adam Monsalve
Keywords(s): Biomedical Engineering, Growth factors, magnetic, Nanoparticles, regenerative medicine, Tissue Engineering
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Research Tools > Therapeutics
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Bottom-Up Tissue Regeneration Scaffold That Rebuilds Tissue Where It Is Needed
Supports Layered Cell Regrowth, Tissue Repair, Fluid Perfusion and Wound Healing to Replace Injured Bone, Muscle and Skin TissuesThis tissue regeneration platform facilitates the layered regrowth of cells to heal traumatic wounds and other injuries by growing bone, muscle, and skin tissues right where they are needed. Regenerative medicine, in which...
Published: 6/27/2021
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Inventor(s): Adam Katz
Keywords(s): Angiogenesis, diffusion, Engineering, microfluidics, regeneration, stem cells, Tissue, Tissue Engineering
Category(s): Technology Classifications > Engineering, Technology Classifications > Human Health Care, Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Medical Devices
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Use of Apoptotic Drug to Improve Scaffolds for Tissue Regeneration
Improved Decellularization Maintains Integrity of Tissue Extracellular Matrix while Maintaining Low Manufacturing CostsThis gentle decellularization process uses an apoptotic drug that enhances production of acellular scaffolds for tissue regeneration and nerve repair. Available technologies for obtaining tissue-specific scaffolds require large volumes...
Published: 6/27/2021
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Inventor(s): Christine Schmidt, Robert Cornelison, Rebecca Wachs
Keywords(s): acellular nerve graft, acellular nucleus pulposus, Acellular scaffold, Apoptosis, Decellularized tissue scaffold, Intervertebral disc, nerve repair, Nucleus Pulpsus Replacement, Peripheral Nerve, Tissue Engineering
Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Engineering > Others, Technology Classifications > Human Health Care > Others
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