This molecular antagonist has been shown to prevent morphine-seeking behavior in animals and may be an effective treatment for opioid addiction in humans . The Center for Disease Control and Prevention estimates that opioid prescription misuse accounts for $78.5 billion in economic burden, and in 2019 alone, nearly 50,000 people died from opioid overdoses. , Medication-assisted treatment is effective in helping combat opioid addiction. However, only a handful of medications are available to treat opioid addiction, and more effective treatments are needed to help address the opioid crisis.
Researchers at the University of Florida have developed a small complex molecule that may be an effective treatment for opioid addiction. This molecule is part of a larger chemical library that contains architecturally diverse molecules that may also be useful as anticancer, antibacterial, and antimalarial drug candidates.
Small complex molecule that is an antagonist for the receptor associated with opioid addiction and may be an effective opioid addiction treatment
Medication-assisted treatment is an effective method for combating opioid addiction, but only a few drugs are available for use. This molecular antagonist binds to the HCRTR2 receptor and may be an effective treatment for opioid addiction. This molecule is part of a larger library of chemical architectures derived from the indole alkaloid, Vincamine. Other molecules in the library may be anticancer, antibacterial, and antimalarial drug candidates.
