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Therapeutic Nanoparticles for Non-Viral Drug Delivery to Natural Killer Cells
Transfects Natural Killer Cells Without the Use of VirusesThese nanoparticles enable the delivery of nucleic acids or drugs to immunosuppressed natural killer (NK) cells to restore their cytotoxic functions in tumor microenvironments. Globally, cancer causes one of every six deaths, with the number of new cases expected to rise to 23.6 million per year...
Published: 6/27/2021
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Inventor(s): Blanka Sharma, Isaac Adjei
Keywords(s): Drug Delivery, Immunotherapy, MNO2, Nanoparticle, Natural Killer Cells, nucleic acid delivery
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Human Health Care > Drug Delivery
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Polymeric Microparticle Blends for Enhanced Cytosolic Drug Delivery
Increase Therapeutic Effects of Drug Delivering MicroparticlesDrug delivery systems utilizing microparticle blends that incorporate poly(propylacrylic acid) into poly(lactide-co-glycolide) improve intracellular cytosolic delivery of bioactive molecules. The therapeutic potential of bioactive molecules delivered by microparticles is reduced considerably...
Published: 6/27/2021
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Inventor(s): Benjamin Keselowsky, Jamal Lewis, Lawrence Fernando, Lirong Yang, Craig Duvall, Brian Evans
Keywords(s): Drug Delivery, Drug Delivery (controlled), Drug Delivery into Cells, Lysosomal ph, Nano/Micro Particles
Category(s): Technology Classifications > Human Health Care > Drug Delivery
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Ophthalmic Formulation That Improves Stability of Cystinosis Treatments
Increases Shelf Life of Cysteamine by Delaying Its Oxidation RateThis eye-drop formulation can increase the effectiveness of ocular cystinosis treatments by delaying the oxidation rate of cysteamine to increase the shelf life of eye-drop products. Cystinosis is a rare genetic disorder that causes crystalline deposits to accumulate in the cornea, negatively...
Published: 6/27/2021
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Inventor(s): Anuj Chauhan, Phillip Dixon
Keywords(s): Drug Delivery, eye drops, Oxygen Resistant Material, Stability
Category(s): Technology Classifications > Engineering > Chemical
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Organically Pigmented Contact Lenses for Ocular Therapeutics
Tints Lenses with Food-Extracted Nanoparticles to Treat Visual Disorders and Protect Against Light, Microbes, and OxidantsThese tinted contact lenses integrate food-derived materials to create unicolor lenses that can block the desired wavelengths of light in order to treat light sensitivity conditions and additionally provide anti-microbial and anti-oxidant...
Published: 6/27/2021
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Inventor(s): Anuj Chauhan, Poorvajan Sekar
Keywords(s): color, Contact Lenses, Drug Delivery, therapeutic lenses
Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Medical Devices > Consumable
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