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Panel of Monoclonal Antibodies for Characterization of AAV8 and AAV9 Capsids to Improve Therapeutic Efficacy of AAV Gene-Based Therapy More Accurately Characterizes AAV8 and AAV9 Capsids for Development of Next Generation Vectors to Evade the Host's Immune Response This panel of antibodies allows better characterization of antigenic epitopes on AAV8 and AAV9 capsids with the goal of mitigating patient immune response to the existing AAV based gene therapy. Adeno-associated viral (AAV)... Published: 6/27/2021   |   Inventor(s): Mavis Agbandje-McKenna, Kim Van Vliet, Yu-Shan Tseng Keywords(s): AAV Vectors, Antibody, Antibody-based assay, dot blot, Elisa, Hybridoma Category(s): Technology Classifications > Research Tools > Biological Materials

Monoclonal Antibody against Connective Tissue Growth Factor Belongs to the CTGF/Cyr61/Cef10/NOVH Protein FamilyConnective Tissue Growth Factor (CTGF) belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF (Connective Tissue Growth factor) is a cysteine-rich, matrix-associated, heparin-binding protein. In vitro,... Published: 6/27/2021   |   Inventor(s): Gregory Schultz, Daniel Gibson, John Azeke, Priscilla Phillips, Edith Sampson, Paulette Robinson Keywords(s): Antibody, CTGF, Elisa, Immunochemistry, Monoclonal, reagent Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Biological Materials, Technology Classifications > Research Tools > Others