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Chimeric Antigen Receptors T-Cell Therapeutics for Better Cancer Therapy
Specific Cytoplasmic Domains Increase Safety, the Signal Specificity and the Killing Efficacy of CAR T-CellsThese chimeric antigen receptors (CARs) include cytoplasmic domains that allow for targeting of specific cells, including autoimmune and cancer cells. Chimeric antigen receptors have the ability to graft onto immune effector cells such as T-cells...
Published: 6/27/2021   |   Inventor(s): Lung-Ji Chang, Jan Moreb
Keywords(s): Antibody, blood cancer, Cancer, dendritic cell, Mulitiple myeloma, T cell, T regulatory cell, Vaccine
Category(s): Technology Classifications > Human Health Care > Therapeutics
Compositions to Enhance Vaccine Efficacy on Mucosal Surfaces
Targeting moDC to Improve Mucosal Surface ProtectionThis composition targets a subset of dendritic cells that mediate cyclic dinucleotide adjuvant activity, thereby improving mucosal surface protection and response to vaccines. In the 20th century, immunization has allowed us to control several life threatening diseases such as measles, whooping cough,...
Published: 9/3/2021   |   Inventor(s):  
Keywords(s): Dendritic Cells, mucosal, prevention, Vaccine, vaccine adjuvant
Category(s): Technology Classifications > Human Health Care > Therapeutics