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Monoclonal Antibodies against Heterogeneous Nuclear Ribonuclear Proteins (hnRNP) m3/4 & m1-4
Recognize hnRNP-M3 As WellHeterogeneous nuclear ribonucleoproteins (hnRNPs), which directly bind to nascent RNA polymerase II transcripts, play an important role in both transcript-specific packaging and alternative splicing of pre-mRNAs. These "M proteins" are pre-mRNA-binding proteins in vivo, and they bind to poly(G) and poly(U) RNA homopolymers...
Published: 7/12/2022
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Inventor(s): Maurice Swanson
Keywords(s):
Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Others
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Monoclonal Antibody against Connective Tissue Growth Factor
Belongs to the CTGF/Cyr61/Cef10/NOVH Protein FamilyConnective Tissue Growth Factor (CTGF) belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF (Connective Tissue Growth factor) is a cysteine-rich, matrix-associated, heparin-binding protein. In vitro,...
Published: 6/27/2021
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Inventor(s): Gregory Schultz, Daniel Gibson, John Azeke, Priscilla Phillips, Edith Sampson, Paulette Robinson
Keywords(s): Antibody, CTGF, Elisa, Immunochemistry, Monoclonal, reagent
Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Biological Materials, Technology Classifications > Research Tools > Others
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Monoclonal Antibody against Trinucleotide TNGW1 (TNRC6G)
RNA Interference with GW182 Results in Translation SuppressionRNA interference (RNAi), triggered by small interfering RNA and microRNA (miRNA), is a potent mechanism in post-transcriptional regulation for gene expression. GW182 is a 182kDa protein which binds to the 3’ untranslated region of mRNA targeted by miRNA and resulting in translation...
Published: 2/22/2024
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Inventor(s): Edward Chan, Songqing Li
Keywords(s): Antibody, GW182, Human, Monoclonal, reagent, RNA Interence, Translational Repression
Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Biological Materials, Technology Classifications > Research Tools > Others
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Monoclonal Antibody against Phosphorylated RAX/PACT Protein
Peptide Compose of RAX Amino Acides Used as Antigen to AntibodyMurine RAX (PKR Activator X) protein and its human ortholog PACT (Protein Activator of Interferon-induced Protein Kinase) are the only known cellular activators of the interferon-induced dsRNA-dependent protein kinase, PKR. RAX and PACT are 98% identical in amino acid sequence. In addition,...
Published: 7/12/2022
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Inventor(s): Richard Bennett, William May
Keywords(s): Antibody, Apoptosis, Monoclonal, Monoclonals, Mouse, PACT, RAX, Tumor
Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Biological Materials, Technology Classifications > Research Tools > Others
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Monoclonal antibodies targeting enzyme involved in silencing mRNA, proteins associated with liver cancer, tumor growth and post-transcription gene silencing
Monoclonal Antibody against p62/IGF2BP2p62/IGF2BP2 is a cytoplasmic mRNA binding protein which binds to mRNA encoding IGF-II and may be involved in hepatic carcinogenesis because autoantibodies are found in a large percentage of patients with hepatocellular carcinoma. MAb were generated using the full length recombinant human protein as antigen. Monoclonal...
Published: 7/12/2022
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Inventor(s): Edward Chan
Keywords(s): Antibody, Human, Monoclonals, RNA, Tumor
Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Biological Materials, Technology Classifications > Research Tools > Others
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Monoclonal Antibody against CUGBP2/ETR-3 Proteins
Recognizes Both Human and Mouse CUGBP2/ETR-3 Proteins but Does Not Bind to Other CELF Family MembersCUGBP2/ETR-3 is a member of the CELF family of pre-mRNA alternative splicing factors which play an important role in the appearance of specific protein isoforms during postnatal development. The CELF family has also been implicated in the neuromuscular...
Published: 7/12/2022
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Inventor(s): Maurice Swanson
Keywords(s): Antibody, COX2, CUGBP2, Monoclonals, Myotonic Dystrophy, RNA Splicing, RNA Turnover
Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Biological Materials, Technology Classifications > Research Tools > Others
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Monoclonal Antibody against Human Calcium-Sensing Receptor
Determines Extracellular Levels of Calcium to Determine Intake Levels of Calcium for CellsThe calcium-sensing receptor detects extracellular levels of calcium to determine the intake levels of calcium for cells. A monoclonal antibody was raised against the extracellular N-terminus of the human calcium-sensing receptor and recognizes human, mouse, rat,...
Published: 7/12/2022
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Inventor(s): Richard Miller
Keywords(s): Antibody, Calcium-sensing Receptor, Cell signaling, G protein, Monoclonals
Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Biological Materials, Technology Classifications > Research Tools > Others
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Monoclonal Antibodies against Limulus Visual Arrestin
Antibodies Are Specific for Limulus-Wide SpeciesThese monoclonal antibodies (4 different hybridomas) were raised against the N-terminal half of recombinant Limulus (horseshoe crab) visual arrestin, a protein that interrupts light-activated signal transduction in the eye, causing an autoimmune eye disorder. Antibodies are specific for Limulus-wide species;...
Published: 2/22/2024
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Inventor(s): Barbara-Anne Battelle, Wesley Smith
Keywords(s):
Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Biological Materials, Technology Classifications > Research Tools > Others
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Monoclonal Antibodies against Yeast RNA- and DNA-Binding Proteins (e.g. PUB1, PAB1, NAB2p)
PUB1, targeting protein that aids in RNA translation and exportPolyuridylate-binding protein (PUB1) is a member of the ribonuclear protein consensus sequence family of RNA-binding proteins and is structurally related to the human heterologous nuclear RNA-binding proteins (hnRNP) M proteins. PUB1 is localized in a non-uniform pattern throughout both...
Published: 7/12/2022
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Inventor(s): Maurice Swanson
Keywords(s):
Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Biological Materials, Technology Classifications > Research Tools > Others
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