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Viscoelastic Clot Strength Predictions from Blood Protein Concentrations
Leverages Rapid Blood Protein Measurements to Accurately Predict Clot Strength and Degradation Speed
This blood viscoelasticity assay predicts clot strength from blood protein concentration levels. Trauma is the primary cause of death for people between the ages of 1 and 44, with coagulation and inflammation biology driving most deaths. Clot mechanical...
Published: 8/7/2025
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Inventor(s): Amor Menezes, Damon Ghetmiri
Keywords(s):
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Software > Healthcare IT
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Advanced Image Restoration for Low-Dose Medical Scans Using Cyclic Simulation and Denoising
Optimizing Medical Imaging Through Radiation Reduction and Advanced Denoising
This data-driven framework combines a simulation processor and a denoiser model to transform low-dose, noisy medical scans into high-quality images to reduce patients’ exposure to radiation. While medical imaging is crucial for diagnosing and monitoring diseases, the...
Published: 7/10/2025
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Inventor(s): Ruogu Fang, Peng Liu
Keywords(s):
Category(s): Technology Classifications > Human Health Care > Diagnostics
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Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay
Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis
This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...
Published: 5/30/2025
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Inventor(s): Yong Zeng, He Yan
Keywords(s):
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics
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Kidney Graft Quality Assessment via Cell-free DNA Quantification in Hypothermic Machine Perfusate
Provides Physicians with a Repeatable and Standardized Approach to Assessing Transplant Quality
This prognostic marker assesses kidney graft quality to provide insights into preservation and post-transplant organ function. Cell-free DNA concentration in kidney allograft perfusate serves as a rapid biomarker that can be used alongside hypothermic machine...
Published: 3/31/2025
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Inventor(s): Sergio Duarte, Narendra Battula, Matthew Willman
Keywords(s):
Category(s): Technology Classifications > Human Health Care > Diagnostics
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Enzymatic Reactions for Modifying and Labeling Extracellular Vesicles
Applies Enzymatic Glycan Engineering to Functionalize and Tag Extracellular Vesicles
This method for modifying extracellular vesicles combines enzymatic glycan engineering with chemoselective functionalization to unlock applications such as targeted drug delivery. Extracellular vesicles are lipid bilayer-enclosed nanoparticles secreted by cells, acting...
Published: 3/27/2025
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Inventor(s): Zhongwu Guo, Mohit Jaiswal, Yong Zeng, Xin Zhou, Jiatong Guo
Keywords(s):
Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Human Health Care > Diagnostics
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3D-Printed Extracellular Vesicles (EVs) for DNA/RNA Sequencing
Enables Single Vesicle DNA/RNA Sequencing to Differentiate Sub-Populations of Extracellular Vesicles (EVs)
These 3D-printed extracellular vesicle (EV) droplets enable DNA and RNA sequencing to differentiate extracellular vesicle subpopulations. Extracellular vesicles are nanosized vesicles containing a variety of cargo, including mRNA, proteins, and...
Published: 9/4/2024
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Inventor(s): Thomas Schmittgen, Thomas Angelini, Andrew Brock, Jinmai Jiang, Senthilkumar Duraivel
Keywords(s):
Category(s): Technology Classifications > Human Health Care > Others, Technology Classifications > Human Health Care, Technology Classifications > Human Health Care > Diagnostics
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Electroencephalography (EEG) Artifact-Removing Algorithm
Uses Reference Noise Recordings to Isolate and Remove EEG-Corrupting Artifacts in Real-Time
This algorithm isolates and removes artifacts from electroencephalography (EEG) recordings in real-time, enabling the acquisition of clean data signals. EEG hardware is an essential tool for detecting brain waves in real-world mobile environments with high temporal...
Published: 9/3/2024
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Inventor(s): Ryan Downey
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Equipment, Technology Classifications > Human Health Care > Diagnostics
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Non-Invasive Machine Learning Software for Diagnosing Parkinson's Disease
Uses Blood Vessel Patterns Taken from Retinal Fundus Images to Predict an Onset or Presence of Parkinson’s Disease
This non-invasive machine learning software uses fundus retinal images to predict the onset or presence of Parkinson’s disease (PD). Parkinson’s disease is the second most common neurodegenerative disorder, affecting...
Published: 9/3/2024
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Inventor(s): Ruogu Fang, Maximillian Diaz
Keywords(s):
Category(s): Technology Classifications > Human Health Care > Diagnostics
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High-Yield Synthesis of Glycosphingolipids
Enables Simple and Efficient Synthesis of Various Glycosphingolipids and their Derivatives for Diagnostic and Biological Applications
This strategy enables the diversity-oriented synthesis of various glycosphingolipids (GSLs). GSLs are a family of glycolipids with a sphingoid or a ceramide as the hydrophobic moiety linked to the downstream end of a...
Published: 9/3/2024
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Inventor(s): Zhongwu Guo, Qingjiang Li
Keywords(s):
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Human Health Care > Therapeutics
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Rapid Diagnostic Test for Detecting Bacterial Infections
Uses Nucleic Acid Amplification to Accurately Detect Virtually All Bacterial Species in Clinical Samples
This rapid PCR-based test uses nucleic acid amplification to quickly and accurately detect harmful bacteria from blood samples without producing false positives. Bloodstream infections (BSI) are among the most severe manifestations of bacterial...
Published: 1/30/2024
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Inventor(s): Kenneth Rand, Herbert Houck
Keywords(s):
Category(s): Technology Classifications > Human Health Care > Others, Technology Classifications > Human Health Care, Technology Classifications > Human Health Care > Diagnostics
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